Li-Ching Chen Selected Research

apiole

7/2019	Study of the antitumor mechanisms of apiole derivatives (AP-02) from Petroselinum crispum through induction of G0/G1 phase cell cycle arrest in human COLO 205 cancer cells.
10/2012	The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate.

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Li-Ching Chen Research Topics

Disease

33	Neoplasms (Cancer) 12/2021 - 08/2002
17	Breast Neoplasms (Breast Cancer) 12/2021 - 06/2010
8	Neoplasm Metastasis (Metastasis) 12/2019 - 06/2005
8	Colonic Neoplasms (Colon Cancer) 07/2019 - 08/2003
5	Triple Negative Breast Neoplasms 12/2021 - 08/2015
5	Carcinogenesis 01/2019 - 06/2005
3	Hepatocellular Carcinoma (Hepatoma) 03/2013 - 08/2009
2	Inflammation (Inflammations) 05/2022 - 03/2017
2	Glioblastoma (Glioblastoma Multiforme) 03/2013 - 08/2009
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2013 - 01/2012
2	Intracranial Vasospasm 01/2013 - 01/2012
2	Body Weight (Weight, Body) 10/2012 - 04/2012
1	Psoriasis (Pustulosis Palmaris et Plantaris) 05/2022
1	Dermatitis 05/2022
1	Chronic Brain Injury 06/2021
1	Brain Injuries (Brain Injury) 06/2021
1	COVID-19 01/2021
1	Melanoma (Melanoma, Malignant) 12/2019
1	Neuroblastoma 01/2019
1	Obesity 01/2017

Drug/Important Bio-Agent (IBA)

13	Messenger RNA (mRNA)IBA 12/2021 - 06/2010
13	Proteins (Proteins, Gene)FDA Link 12/2021 - 08/2002
8	Nicotine FDA Link 12/2019 - 09/2010
5	Small Interfering RNA (siRNA)IBA 08/2015 - 06/2010
4	PolyphenolsIBA 01/2021 - 03/2011
4	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 12/2019 - 09/2010
3	TeaIBA 01/2021 - 03/2011
3	Cadherins (E-Cadherin)IBA 12/2019 - 01/2018
3	Estrogens (Estrogen)FDA Link 01/2019 - 03/2011
3	Estrogen ReceptorsIBA 10/2018 - 06/2010
3	Cholinergic ReceptorsIBA 11/2016 - 03/2011
3	EnzymesIBA 08/2015 - 06/2010
3	magnololIBA 03/2013 - 08/2009
2	Hyaluronan SynthasesIBA 10/2021 - 01/2019
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2018
2	Focal Adhesion Protein-Tyrosine KinasesIBA 12/2019 - 08/2012
2	PaxillinIBA 12/2019 - 08/2012
2	apioleIBA 07/2019 - 10/2012
2	SmokeIBA 01/2019 - 06/2005
2	Tamoxifen FDA LinkGeneric 11/2018 - 06/2010
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2018 - 09/2016
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 03/2017
2	PhloretinIBA 01/2018 - 09/2016
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2018 - 09/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 09/2016
2	garcinolIBA 03/2017 - 01/2011
2	Cyclin-Dependent Kinase Inhibitor p27IBA 04/2012 - 05/2003
2	Cyclin D3IBA 01/2011 - 08/2002
2	AgarIBA 01/2011 - 09/2010
2	CarcinogensIBA 09/2010 - 06/2005
2	Terbinafine (Lamisil)FDA LinkGeneric 05/2008 - 08/2003
2	CaspasesIBA 07/2006 - 10/2005
1	phenolic acidIBA 05/2022
1	AcidsIBA 05/2022
1	Imiquimod (Aldara)FDA LinkGeneric 05/2022
1	lithospermic acidIBA 05/2022
1	SaltsIBA 12/2021
1	CurcuminIBA 12/2021
1	Cyclin DIBA 12/2021
1	Hyaluronic Acid (Hyaluronan)IBA 10/2021
1	Insulin Receptor Substrate ProteinsIBA 06/2021
1	Tight Junction ProteinsIBA 06/2021
1	mRNA VaccinesIBA 01/2021
1	Proline Oxidase (Proline Dehydrogenase)IBA 01/2021
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2021
1	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 12/2019
1	Monomeric GTP-Binding ProteinsIBA 12/2019
1	CateninsIBA 12/2019
1	Histone Deacetylase InhibitorsIBA 11/2019
1	Cyclin D1IBA 07/2019
1	Adenosine Triphosphatases (ATPase)IBA 04/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2019
1	UbiquitinIBA 04/2019
1	human ERBB2 proteinIBA 04/2019
1	NitrosaminesIBA 01/2019
1	MelatoninIBA 01/2019
1	DNA Primase (Primase)IBA 01/2019
1	Peptides (Polypeptides)IBA 01/2019
1	Bupropion (Wellbutrin)FDA LinkGeneric 01/2019
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019
1	inotiloneIBA 01/2019
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2018
1	Glutathione Transferase (Glutathione S-Transferase)IBA 11/2018
1	Nuclear Proteins (Protein, Nuclear)IBA 10/2018
1	Phenobarbital (Luminal)FDA Link 10/2018
1	Boronic AcidsIBA 01/2018
1	VimentinIBA 01/2018
1	PolymersIBA 01/2018
1	Paclitaxel (Taxol)FDA LinkGeneric 03/2017
1	Caspase 3 (Caspase-3)IBA 03/2017
1	Twist-Related Protein 1IBA 03/2017
1	Phospholipases A2 (Phospholipase A2)IBA 03/2017
1	Biological ProductsIBA 01/2017
1	FlavonoidsIBA 01/2017
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 11/2016

Therapy/Procedure

10	Therapeutics 12/2021 - 08/2002
4	Drug Therapy (Chemotherapy) 12/2021 - 08/2002
2	Lasers (Laser) 09/2010 - 06/2010
1	Heterologous Transplantation (Xenotransplantation) 10/2021
1	Radiotherapy 11/2019